Can You Overdose on Promethazine? Understanding the Risks

Promethazine is an ingredient in codeine-based recreational opioid drinks used by many rappers
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Promethazine is a medication that’s commonly prescribed for various conditions, but like many pharmaceuticals, it carries risks when misused. At The Bluffs Addiction Campuses in Ohio, we believe in educating our community about the dangers of drug misuse, including prescription medications like promethazine. This article will explore the risks associated with promethazine use and the potential for overdose.

What is Promethazine and What Are Its Intended Uses?

Promethazine is an antihistamine medication primarily used to treat allergies, motion sickness, and nausea. It’s also sometimes used as a sedative or to enhance the effects of pain medications. Common brand names include Phenergan and Promethegan. While it’s generally safe when used as prescribed, promethazine can be dangerous if misused or taken in large quantities.

Effects of Promethazine on the Body

Promethazine affects the body in several ways:

  • Blocks histamine receptors, reducing allergy symptoms
  • Acts on the brain to prevent nausea and vomiting
  • Causes drowsiness and sedation
  • Can have a calming effect on the central nervous system

Signs and Symptoms of Promethazine Overdose

Yes, it is possible to overdose on promethazine. Signs of a promethazine overdose may include:

  • Severe drowsiness or loss of consciousness
  • Difficulty breathing or shallow breathing
  • Seizures
  • Hallucinations
  • Agitation or confusion
  • Dilated pupils
  • Dry mouth
  • Flushed skin
  • Rapid heartbeat
  • In severe cases, coma or death

Dangers of Mixing Promethazine with Other Substances

The risks of promethazine increase significantly when it’s combined with other substances, particularly:

Opioids

Mixing promethazine with opioids can dangerously increase sedation and depress respiratory function, potentially leading to life-threatening complications.

Alcohol

Combining promethazine with alcohol can intensify the sedative effects of both substances, increasing the risk of overdose and other adverse reactions.

Potential for Promethazine Abuse and Addiction

While promethazine itself is not considered addictive, it’s often misused in combination with other substances, particularly codeine (as in “purple drank” or “lean”). This combination can lead to a pattern of abuse and addiction. Some individuals may also develop a psychological dependence on promethazine’s sedative effects.

Promethazine is one of the key ingredients in the popular "purple drank"
Promethazine is one of the key ingredients in the popular “purple drank”

Treatment Options for Promethazine Misuse

At The Bluffs, we offer comprehensive treatment for individuals struggling with promethazine misuse or addiction to substances often combined with promethazine. Our approach includes:

  • Medically supervised detoxification
  • Individual and group therapy to address underlying issues
  • Cognitive-behavioral therapy to change harmful thought patterns and behaviors
  • Education about the risks of prescription drug misuse
  • Holistic therapies to support overall well-being
  • Aftercare planning to support long-term recovery

The Bluffs’ Approach to Prescription Drug Misuse

Our treatment programs at The Bluffs are designed to address the complex nature of prescription drug misuse and polysubstance abuse. We recognize that many individuals who misuse promethazine may also be struggling with other substance use issues or mental health disorders. Our approach includes:

  • Comprehensive assessment to identify all substances being misused
  • Dual diagnosis treatment for co-occurring mental health disorders
  • Personalized treatment plans that address each individual’s unique needs
  • Family therapy to heal relationships and build a strong support system

Seeking Help for Promethazine Overdose or Misuse

If you suspect someone is experiencing a promethazine overdose, it’s crucial to seek emergency medical attention immediately by calling 911. Signs of overdose should always be treated as a medical emergency.

For those struggling with promethazine misuse or addiction to substances often combined with promethazine, help is available. At The Bluffs Addiction Campuses, we’re committed to supporting individuals through every step of their recovery journey.

Don’t let promethazine misuse control your life or the life of someone you love. Call us today at 850-374-5331 to speak with one of our addiction specialists. We’re here to answer your questions, provide support, and help you start on the path to recovery. Your journey towards a healthier, substance-free life can begin right now.

The Bluffs is a private alcohol, substance abuse and mental health treatment facility located in central Ohio.

The central Ohio location means we are also just a short drive (or even shorter flight) from Pittsburgh and other parts of Pennsylvania, New York, West Virginia, Kentucky, Indiana and Michigan.

We offer alcohol and drug detox services, dual-diagnosis addiction treatment, medication-assisted treatment (MAT) and more.

Our goal is always to minimize the out-of-pocket costs for patients coming to The Bluffs. We work with many major health insurance plans and providers such as America’s Choice Provider Network, Anthem, Beacon Health Options, BlueCross BlueShield, First Health Network, Humana, Magellan Health, Medical Mutual of Ohio, Mercy Health, OhioHealth, Prime Healthcare, UPMC Health Plan, and the Ohio Department of Veteran Services

Contact The Bluffs Now

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